Tau phosphorylation in cells transfected with wild-type or an Alzheimer's disease mutant Presenilin 1.

We have studied the effect of overexpressing either wild-type or an Alzheimer's disease mutant Presenilin 1 (PS1) on tau phosphorylation in transfected Chinese hamster ovary (CHO) and COS cells. Tau transfected into these cells is predominantly non-phosphorylated at many PHF-tau sites but co-tr...

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Main Authors: Irving, N, Miller, C
格式: Journal article
語言:English
出版: 1997