Investigating the complex arrhythmic phenotype caused by the gain-of-function mutation KCNQ1-G229D
The congenital long QT syndrome (LQTS) is a cardiac electrophysiological disorder that can cause sudden cardiac death. LQT1 is a subtype of LQTS caused by mutations in KCNQ1, affecting the slow delayed-rectifier potassium current (IKs), which is essential for cardiac repolarization. Paradoxically, g...
| Үндсэн зохиолчид: | , , , , , , , , , |
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| Формат: | Journal article |
| Хэвлэсэн: |
Frontiers Media
2019
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