Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage

Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage

Manylion Llyfryddiaeth
Prif Awduron:	Troeberg, L, Nagase, H
Fformat:	Journal article
Cyhoeddwyd:	2009

Eitemau Tebyg

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.
gan: Troeberg, L, et al.
Cyhoeddwyd: (2008)

Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change
gan: Troeberg, L, et al.
Cyhoeddwyd: (2010)

What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?
gan: Troeberg, L, et al.
Cyhoeddwyd: (2009)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
gan: Troeberg, L, et al.
Cyhoeddwyd: (2012)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
gan: Troeberg, L, et al.
Cyhoeddwyd: (2012)

TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5).
gan: Kashiwagi, M, et al.
Cyhoeddwyd: (2001)

Aggrecanases in cartilage matrix breakdown
gan: Nagase, H
Cyhoeddwyd: (2001)

Aggrecanases and cartilage matrix degradation.
gan: Nagase, H, et al.
Cyhoeddwyd: (2003)

Aggrecanases and TIMP-3 in osteoarthritis: structure, function and in vivo challenges
gan: Nagase, H
Cyhoeddwyd: (2009)

Pentosan Polysulfate Maculopathy—Prescribers Should Be Aware
gan: Yusuf, IH, et al.
Cyhoeddwyd: (2020)

TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors.
gan: Gendron, C, et al.
Cyhoeddwyd: (2003)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
gan: Fuming Zhang, et al.
Cyhoeddwyd: (2022-02-01)

Potentiation of carbon tetrachloride hepatotoxicity by pentosan polysulfate in rats
gan: Zim M.C.A., et al.
Cyhoeddwyd: (2002-01-01)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
gan: Margaret M. Smith, et al.
Cyhoeddwyd: (2023-03-01)

Use of Pentosan Polysulfate in the Local Treatment of Reactive Arthritis in Children
gan: O.A. Danylov, et al.
Cyhoeddwyd: (2016-05-01)

Tenascin-C fragments induce aggrecanase activity in cartilage
gan: Sofat, N, et al.
Cyhoeddwyd: (2008)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
gan: Elodie Bousquet, et al.
Cyhoeddwyd: (2023-03-01)

Effectiveness of oral pentosan polysulfate in painful bladder syndrome: Is it worth the cost?
gan: Devdatt Purushottam Palnitkar, et al.
Cyhoeddwyd: (2021-01-01)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
gan: Kalbag NS, et al.
Cyhoeddwyd: (2021-02-01)

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis
gan: Hiroyuki Nakamura, et al.
Cyhoeddwyd: (2020-06-01)

Advanced pentosan polysulfate sodium maculopathy with low cumulative exposure and hydroxychloroquine use
gan: Elena Flester, et al.
Cyhoeddwyd: (2024-12-01)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
gan: Miranda X Tong, et al.
Cyhoeddwyd: (2021-11-01)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
gan: Leung EH, et al.
Cyhoeddwyd: (2021-12-01)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease.
gan: Andrea N Crivaro, et al.
Cyhoeddwyd: (2019-01-01)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
gan: Alekseeva, Anna, et al.
Cyhoeddwyd: (2021)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
gan: Alekseeva, Anna, et al.
Cyhoeddwyd: (2022)

Retrospective study of incidence/prevalence of pigmentary maculopathy and retinopathy in patients receiving pentosan polysulfate sodium.
gan: Zhong Yuan, et al.
Cyhoeddwyd: (2025-01-01)

An unusual case of rapid resolution of bilateral vitelliform deposits after discontinuation of pentosan polysulfate sodium
gan: Fritz Gerald P. Kalaw, et al.
Cyhoeddwyd: (2023-12-01)

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate
gan: Margaret M. Smith, et al.
Cyhoeddwyd: (2022-09-01)

Screening practices and risk assessment for maculopathy in pentosan polysulfate users across different exposure levels
gan: Hyeon Yoon Kwon, et al.
Cyhoeddwyd: (2024-05-01)

Collagenases and aggrecanases: understanding the role of non-catalytic domains in cartilage matrix breakdown
gan: Nagase, H, et al.
Cyhoeddwyd: (2005)

Analysis of TIMP expression and activity.
gan: Troeberg, L, et al.
Cyhoeddwyd: (2007)

Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3 (TIMP-3)
gan: Chanalaris, A, et al.
Cyhoeddwyd: (2017)

Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study
gan: Yulin Hswen, et al.
Cyhoeddwyd: (2025-01-01)

Pigmentary Maculopathy in Interstitial Cystitis/Bladder Pain Syndrome Treated with Oral Pentosan Polysulfate: A Review
gan: Richard Parkinson, et al.
Cyhoeddwyd: (2022-09-01)

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow
gan: H. M. Suranji Wijekoon, et al.
Cyhoeddwyd: (2018-05-01)

E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A).
gan: Troeberg, L, et al.
Cyhoeddwyd: (2002)

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity
gan: Lo Cicero, A, et al.
Cyhoeddwyd: (2012)

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity.
gan: Lo Cicero, A, et al.
Cyhoeddwyd: (2012)

Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
gan: Lindsay A. Parker, et al.
Cyhoeddwyd: (2022-01-01)