Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage

Calcium pentosan polysulfate is a multi-functional aggrecanase inhibitor that enhances interaction with endogenous TIMP-3 in cartilage

Bibliografski detalji
Glavni autori:	Troeberg, L, Nagase, H
Format:	Journal article
Izdano:	2009

Slični predmeti

Calcium pentosan polysulfate is a multifaceted exosite inhibitor of aggrecanases.
od: Troeberg, L, i dr.
Izdano: (2008)

Calcium pentosan polysulfate increases affinity between aggrecanases (ADAMTS-4 and-5) and TIMP-3 by a conformational change
od: Troeberg, L, i dr.
Izdano: (2010)

What is the minimal length of calcium pentosan polysulfate that is able to block aggrecan breakdown in cartilage?
od: Troeberg, L, i dr.
Izdano: (2009)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex
od: Troeberg, L, i dr.
Izdano: (2012)

Pentosan polysulfate increases affinity between ADAMTS-5 and TIMP-3 through formation of an electrostatically driven trimolecular complex.
od: Troeberg, L, i dr.
Izdano: (2012)

TIMP-3 is a potent inhibitor of aggrecanase 1 (ADAM-TS4) and aggrecanase 2 (ADAM-TS5).
od: Kashiwagi, M, i dr.
Izdano: (2001)

Aggrecanases in cartilage matrix breakdown
od: Nagase, H
Izdano: (2001)

Aggrecanases and cartilage matrix degradation.
od: Nagase, H, i dr.
Izdano: (2003)

Aggrecanases and TIMP-3 in osteoarthritis: structure, function and in vivo challenges
od: Nagase, H
Izdano: (2009)

Pentosan Polysulfate Maculopathy—Prescribers Should Be Aware
od: Yusuf, IH, i dr.
Izdano: (2020)

TIMP-3 inhibits aggrecanase-mediated glycosaminoglycan release from cartilage explants stimulated by catabolic factors.
od: Gendron, C, i dr.
Izdano: (2003)

Potential Anti-SARS-CoV-2 Activity of Pentosan Polysulfate and Mucopolysaccharide Polysulfate
od: Fuming Zhang, i dr.
Izdano: (2022-02-01)

Potentiation of carbon tetrachloride hepatotoxicity by pentosan polysulfate in rats
od: Zim M.C.A., i dr.
Izdano: (2002-01-01)

Pentosan Polysulfate Affords Pleotropic Protection to Multiple Cells and Tissues
od: Margaret M. Smith, i dr.
Izdano: (2023-03-01)

Use of Pentosan Polysulfate in the Local Treatment of Reactive Arthritis in Children
od: O.A. Danylov, i dr.
Izdano: (2016-05-01)

Tenascin-C fragments induce aggrecanase activity in cartilage
od: Sofat, N, i dr.
Izdano: (2008)

Type 3 macular neovascularization in a patient with pentosan polysulfate maculopathy
od: Elodie Bousquet, i dr.
Izdano: (2023-03-01)

Effectiveness of oral pentosan polysulfate in painful bladder syndrome: Is it worth the cost?
od: Devdatt Purushottam Palnitkar, i dr.
Izdano: (2021-01-01)

Maculopathy Secondary to Pentosan Polysulfate Use: A Single-Center Experience
od: Kalbag NS, i dr.
Izdano: (2021-02-01)

Aggrecanase-selective tissue inhibitor of metalloproteinase-3 (TIMP3) protects articular cartilage in a surgical mouse model of osteoarthritis
od: Hiroyuki Nakamura, i dr.
Izdano: (2020-06-01)

Advanced pentosan polysulfate sodium maculopathy with low cumulative exposure and hydroxychloroquine use
od: Elena Flester, i dr.
Izdano: (2024-12-01)

Acute and severe haemorrhage following pentosan polysulfate injection in a Cornish Rex
od: Miranda X Tong, i dr.
Izdano: (2021-11-01)

Pentosan Polysulfate Sodium-Associated Pigmentary Retinopathy: Risk Factors and Fundus Findings
od: Leung EH, i dr.
Izdano: (2021-12-01)

Efficacy of pentosan polysulfate in in vitro models of lysosomal storage disorders: Fabry and Gaucher Disease.
od: Andrea N Crivaro, i dr.
Izdano: (2019-01-01)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
od: Alekseeva, Anna, i dr.
Izdano: (2021)

In-depth structural characterization of pentosan polysulfate sodium complex drug using orthogonal analytical tools
od: Alekseeva, Anna, i dr.
Izdano: (2022)

Retrospective study of incidence/prevalence of pigmentary maculopathy and retinopathy in patients receiving pentosan polysulfate sodium.
od: Zhong Yuan, i dr.
Izdano: (2025-01-01)

An unusual case of rapid resolution of bilateral vitelliform deposits after discontinuation of pentosan polysulfate sodium
od: Fritz Gerald P. Kalaw, i dr.
Izdano: (2023-12-01)

Xylan Prebiotics and the Gut Microbiome Promote Health and Wellbeing: Potential Novel Roles for Pentosan Polysulfate
od: Margaret M. Smith, i dr.
Izdano: (2022-09-01)

Screening practices and risk assessment for maculopathy in pentosan polysulfate users across different exposure levels
od: Hyeon Yoon Kwon, i dr.
Izdano: (2024-05-01)

Collagenases and aggrecanases: understanding the role of non-catalytic domains in cartilage matrix breakdown
od: Nagase, H, i dr.
Izdano: (2005)

Analysis of TIMP expression and activity.
od: Troeberg, L, i dr.
Izdano: (2007)

Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3 (TIMP-3)
od: Chanalaris, A, i dr.
Izdano: (2017)

Sentiments of Individuals with Interstitial Cystitis/Bladder Pain Syndrome Toward Pentosan Polysulfate Sodium: Infodemiology Study
od: Yulin Hswen, i dr.
Izdano: (2025-01-01)

Pigmentary Maculopathy in Interstitial Cystitis/Bladder Pain Syndrome Treated with Oral Pentosan Polysulfate: A Review
od: Richard Parkinson, i dr.
Izdano: (2022-09-01)

Inhibitory effects of sodium pentosan polysulfate on formation and function of osteoclasts derived from canine bone marrow
od: H. M. Suranji Wijekoon, i dr.
Izdano: (2018-05-01)

E. coli expression of TIMP-4 and comparative kinetic studies with TIMP-1 and TIMP-2: insights into the interactions of TIMPs and matrix metalloproteinase 2 (gelatinase A).
od: Troeberg, L, i dr.
Izdano: (2002)

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity
od: Lo Cicero, A, i dr.
Izdano: (2012)

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity.
od: Lo Cicero, A, i dr.
Izdano: (2012)

Transient Postoperative Hemorrhage from Elbow Arthroscopy Portals following Intra-Articular Pentosan Polysulfate Sodium Injection
od: Lindsay A. Parker, i dr.
Izdano: (2022-01-01)