Longitudinal changes in glucocorticoid metabolism are associated with later development of adverse metabolic phenotype.

OBJECTIVE: Dysregulation of enzymes that control local tissue steroid metabolism has been implicated in the pathogenesis of obesity and insulin resistance; however, longitudinal changes in glucocorticoid metabolism have not been investigated. This study was performed to evaluate the role of glucocor...

Descripció completa

Dades bibliogràfiques
Autors principals: Crowley, R, Hughes, B, Gray, J, McCarthy, T, Hughes, S, Shackleton, C, Crabtree, N, Nightingale, P, Stewart, P, Tomlinson, J
Format: Journal article
Idioma:English
Publicat: BioScientifica Ltd. 2014