Longitudinal changes in glucocorticoid metabolism are associated with later development of adverse metabolic phenotype.

OBJECTIVE: Dysregulation of enzymes that control local tissue steroid metabolism has been implicated in the pathogenesis of obesity and insulin resistance; however, longitudinal changes in glucocorticoid metabolism have not been investigated. This study was performed to evaluate the role of glucocor...

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Hlavní autoři: Crowley, R, Hughes, B, Gray, J, McCarthy, T, Hughes, S, Shackleton, C, Crabtree, N, Nightingale, P, Stewart, P, Tomlinson, J
Médium: Journal article
Jazyk:English
Vydáno: BioScientifica Ltd. 2014