Structural insights into the binding of cardiac glycosides to the digitalis receptor revealed by solid-state NMR.

Structural insights into the binding of cardiac glycosides to the digitalis receptor revealed by solid-state NMR.

Several biologically active derivatives of the cardiotonic steroid ouabain have been made containing NMR isotopes ((13)C, (2)H, and (19)F) in the rhamnose sugar and steroid moieties, and examined at the digitalis receptor site of renal Na(+)/K(+)-ATPase by a combination of solid-state NMR methods. D...

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Bibliografiske detaljer
Main Authors:	Middleton, D, Rankin, S, Esmann, M, Watts, A
Format:	Journal article
Sprog:	English
Udgivet:	2000

Lignende værker

Solid state NMR studies of ligand conformations in the binding sites of ion translocating APTases
af: Watts, J, et al.
Udgivet: (1999)

Solid state NMR studies of ligand dynamics and conformations is the binding sites of the gastric H+/K+-ATPase
af: Watts, J, et al.
Udgivet: (2000)

Probing the structure and dynamics of acetylcholinesterase inhibitors is the binding site using solid state NMR
af: Goodall, S, et al.
Udgivet: (2000)

G-protein-coupled receptor structure, ligand binding and activation as studied by solid-state NMR spectroscopy.
af: Ding, X, et al.
Udgivet: (2013)

Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor.
af: Grobner, P, et al.
Udgivet: (1998)

Probing the agonist binding pocket in the nicotinic acetylcholine receptor: a high-resolution solid-state NMR approach.
af: Williamson, P, et al.
Udgivet: (1998)

Solid state NMR studies of ligands bound to the nicotinic acetylcholine receptor.
af: Williamson, P, et al.
Udgivet: (1998)

Structural and functional studies of the nicotinic acetylcholine receptor by solid-state NMR.
af: Williamson, P, et al.
Udgivet: (2004)

Membrane protein structure determination by solid state NMR.
af: Watts, A, et al.
Udgivet: (1999)

Membrane protein structure: the contribution and potential of novel solid state NMR approaches.
af: Watts, A, et al.
Udgivet: (1995)

Structural descriptions of ligands in their binding site of integral membrane proteins at near physiological conditions using solid-state NMR
af: Watts, A, et al.
Udgivet: (1998)

Probing the environment of neurotensin whilst bound to the neurotensin receptor by solid state NMR.
af: Williamson, P, et al.
Udgivet: (2002)

Preface: Solid-state NMR on biological systems
af: Watts, A
Udgivet: (2004)

Recent developments in biomolecular solid-state NMR
af: Higman, V, et al.
Udgivet: (2012)

Structure and dynamics in the nucleosome revealed by solid-state NMR
af: Shi, Xiangyan, et al.
Udgivet: (2018)

Effects of adding digitoxigenin and gitoxigenin to the nutrient medium on cardiac glycosides production from digitalis purpurea (Var. Excelsior Mixed) by using tissue culture technique
af: AL–Khateeb H. Ekbal, et al.
Udgivet: (2004-06-01)

Structural studies of prospholamban using solid-state magic-angle spinning (MAS) NMR methods.
af: Ahmed, Z, et al.
Udgivet: (2000)

Probing the structure and mechanism of binding of an inhibitor to a P-type-ATPase and of sugars during translocation by expressed transporters, using solid state MAS NMR.
af: Watts, A, et al.
Udgivet: (1998)

Lipid specificity in the interaction of cytochrome c with anionic phospholipid bilayers revealed by solid-state 31P NMR.
af: Pinheiro, T, et al.
Udgivet: (1994)

Structural resolution of ligand-receptor interactions in functional, membrane-embedded receptors and proteins using novel, non-perturbing solid-state NMR methods
af: Watts, A
Udgivet: (1999)

A solid-state NMR study of the phospholamban transmembrane domain: local structure and interactions with Ca(2+)-ATPase.
af: Ahmed, Z, et al.
Udgivet: (2000)

Solid-state NMR approaches for studying the interaction of peptides and proteins with membranes
af: Watts, A
Udgivet: (1998)

Solid-state NMR in drug design and discovery for membrane-embedded targets.
af: Watts, A
Udgivet: (2005)

Solution- and solid-state NMR studies of GPCRs and their ligands
af: Tapaneeyakorn, S, et al.
Udgivet: (2011)

Solution- and solid-state NMR studies of GPCRs and their ligands.
af: Tapaneeyakorn, S, et al.
Udgivet: (2011)

Zinc-binding structure of a catalytic amyloid from solid-state NMR
af: Lee, Myungwoon, et al.
Udgivet: (2018)

Protein-lipid interactions is bacteriorhodopsin studied by solid state NMR
af: Mason, J, et al.
Udgivet: (2000)

Binding properties of the stilbene disulfonate sites on human erythrocyte AE1: kinetic, thermodynamic, and solid state deuterium NMR analyses.
af: Taylor, A, et al.
Udgivet: (1999)

A model of reversible inhibitors in the gastric H+/K+-ATPase binding site determined by rotational echo double resonance NMR.
af: Watts, J, et al.
Udgivet: (2001)

Zebrafish chemical screening reveals the impairment of dopaminergic neuronal survival by cardiac glycosides.
af: Yaping Sun, et al.
Udgivet: (2012-01-01)

New insights into the bonding arrangements of L- and D-glutamates from solid state O-17 NMR
af: Lemaitre, V, et al.
Udgivet: (2003)

Digitalis intoxication.
af: Aronson, J
Udgivet: (1983)

Excursio digitalis
af: Simon Puschmann
Udgivet: (2021-12-01)

Risorse digitali
af: Redazione Reti Medievali (a cura di)
Udgivet: (2012-01-01)

Risorse digitali
af: Redazione Reti Medievali (a cura di)
Udgivet: (2012-01-01)

Risorse digitali
af: Redazione Reti Medievali (a cura di)
Udgivet: (2008-12-01)

Risorse digitali
af: Redazione Reti Medievali (a cura di)
Udgivet: (2010-06-01)

Risorse digitali
af: Redazione Reti Medievali (a cura di)
Udgivet: (2006-06-01)

Risorse digitali
af: Redazione Reti Medievali (a cura di)
Udgivet: (2009-12-01)

Dissonanze digitali
af: Massimo Canevacci
Udgivet: (2006-06-01)