Ion channels in genetic and acquired forms of epilepsy

Ion channels in genetic and acquired forms of epilepsy

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Genetic mutations causing dysfunction of both voltage- and ligand-gated ion channels make a major contribution to the cause of many different types of familial epilepsy. Key mechanisms comprise defective Na+ channels of inhibitory neurons, or GABAA receptors affecting pre- or postsynaptic GABAergic...

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Huvudupphovsmän: Lerche, H, Shah, M, Beck, H, Noebels, J, Johnston, D, Vincent, A
Materialtyp: Journal article
Publicerad: 2013

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