Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites
Acquired immunity in vertebrates maintains polymorphisms in endemic pathogens, leading to identifiable signatures of balancing selection. To comprehensively survey for genes under such selection in the human malaria parasite Plasmodium falciparum, we generated paired-end short-read sequences of para...
Үндсэн зохиолчид: | Amambua-Ngwa, A, Tetteh, K, Manske, M, Gomez-Escobar, N, Stewart, L, Deerhake, M, Cheeseman, I, Newbold, C, Holder, A, Knuepfer, E, Janha, O, Jallow, M, Campino, S, Macinnis, B, Kwiatkowski, D, Conway, D |
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Формат: | Journal article |
Хэл сонгох: | English |
Хэвлэсэн: |
Public Library of Science
2012
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Ижил төстэй зүйлс
Ижил төстэй зүйлс
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Population genomic scan for candidate signatures of balancing selection to guide antigen characterization in malaria parasites.
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Prospective identification of malaria parasite genes under balancing selection.
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