The von Hippel-Lindau Chuvash mutation in mice alters cardiac substrate and high energy phosphate metabolism

Hypoxia-inducible factor (HIF) appears to function as a global master regulator of cellular and systemic responses to hypoxia. HIF-pathway manipulation is of therapeutic interest, however global, systemic upregulation of HIF may have as yet unknown effects on multiple processes. We utilized a mouse...

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Bibliographic Details
Main Authors: Slingo, M, Cole, M, Carr, C, Curtis, M, Dodd, M, Giles, L, Heather, L, Tyler, D, Clarke, K, Robbins, P
Format: Journal article
Language:English
Published: American Physiological Society 2016