A Concise Synthesis of the Octalactins

A Concise Synthesis of the Octalactins

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The total synthesis of octalactins A and B has been achieved in 15 steps (longest linear sequence) and 10% overall yield from commercially available materials. Key steps include the Paterson-Aldol reaction for the rapid assembly of the carbonate 46, methylenation of 46 and subsequent Claisen rearran...

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Bibliographic Details
Main Authors:	O'Sullivan, P, Buhr, W, Fuhry, M, Harrison, JR, Davies, J, Feeder, N, Marshall, DR, Burton, J, Holmes, AB
Format:	Journal article
Language:	English
Published:	2004

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