Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid

Hydrochlorofluoromethylation of unactivated alkenes with chlorofluoroacetic acid

An operationally simple method enabling hydrochlorofluoromethylation of unactivated alkenes under visible light activation is reported. The procedure has various benefits. It uses commercially available and inexpensive chlorofluoroacetic acid and phenyliodine(III) diacetate for the generation of the...

Full description

Bibliographic Details
Main Authors:	Meyer, CF, Hell, SM, Sap, JBI, Misale, A, Peschiulli, A, Oehlrich, D, Trabanco, AA, Gouverneur, V
Format:	Journal article
Language:	English
Published:	Elsevier 2019

Similar Items

Hydrosulfonylation of alkenes with sulfonyl chlorides under visible light activation
by: Hell, SM, et al.
Published: (2020)

Hydrodifluoromethylation of alkenes with difluoroacetic acid
by: Meyer, C, et al.
Published: (2019)

Hydrofluoromethylation of alkenes with fluoroiodomethane and beyond
by: Hell, SM, et al.
Published: (2021)

Silyl radical-mediated activation of sulfamoyl chlorides enables direct access to aliphatic sulfonamides from alkenes
by: Hell, SM, et al.
Published: (2019)

Catalytic hydrotrifluoromethylation of unactivated alkenes.
by: Mizuta, S, et al.
Published: (2013)

Copper-Catalyzed Oxytrifluoromethylation of Unactivated Alkenes
by: Zhu, Rong, et al.
Published: (2015)

Easy access to aliphatic sulfonamides using sulfamoyl chlorides under visible light activation
by: Hell, SM, et al.
Published: (2020)

Metal-free electrochemical dihydroxylation of unactivated alkenes
by: Min Liu, et al.
Published: (2023-10-01)

2-Alkylation of 3-Alkyindoles With Unactivated Alkenes
by: Xuling Pan, et al.
Published: (2022-02-01)

Late-stage difluoromethylation: concepts, developments and perspective
by: Sap, JBI, et al.
Published: (2021)

Electroreduction of unactivated alkenes using water as hydrogen source
by: Yanwei Wang, et al.
Published: (2024-03-01)

Rhodium-Catalyzed Asymmetric Intramolecular Hydroamination of Unactivated Alkenes
by: Shen, Xiaoqiang, et al.
Published: (2013)

Hydrogen bonding phase-transfer catalysis with ionic reactants: enantioselective synthesis of γ-fluoroamines
by: Roagna, G, et al.
Published: (2020)

Intermolecular reductive heck reaction of unactivated aliphatic alkenes with organohalides
by: Zheng, Kewang, et al.
Published: (2022)

Directed nickel-catalyzed regio- and diastereoselective arylamination of unactivated alkenes
by: Leipeng Xie, et al.
Published: (2021-11-01)

Ru(phen)3Cl2‐Catalyzed Chlorotrifluoromethylation of Unactivated Alkenes
by: Wenhao Su, et al.
Published: (2023-07-01)

Diverse Engineered Heme Proteins Enable Stereodivergent Cyclopropanation of Unactivated Alkenes
by: Anders M. Knight, et al.
Published: (2018-02-01)

Arylcarboxylation of unactivated alkenes with CO2 via visible-light photoredox catalysis
by: Wei Zhang, et al.
Published: (2023-06-01)

Construction of azaheterocycles via Pd-catalyzed migratory cycloannulation reaction of unactivated alkenes
by: Jin-Ping Wang, et al.
Published: (2022-08-01)

Divergent regioselective Heck-type reaction of unactivated alkenes and N-fluoro-sulfonamides
by: Chunyang Zhao, et al.
Published: (2022-10-01)

Ni-catalyzed carbamoylation of unactivated alkenes for stereoselective construction of six-membered lactams
by: Chenhuan Zhang, et al.
Published: (2022-10-01)

Synthesis of 3,3-Disubstituted Heterocycles by Pd-Catalyzed Arylallylation of Unactivated Alkenes
by: David Phillips, et al.
Published: (2018-07-01)

Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes
by: Xiaojuan Li, et al.
Published: (2021-02-01)

Organophotoredox hydrodefluorination of trifluoromethylarenes with translational applicability to drug discovery
by: Sap, JBI, et al.
Published: (2020)

A Catalytic Three‐Component Aminofluorination of Unactivated Alkenes with Electron‐Rich Amino Sources
by: Junchao Dong, et al.
Published: (2024-03-01)

Earth-Abundant 3d Transition Metal Catalysts for Hydroalkoxylation and Hydroamination of Unactivated Alkenes
by: Lou Rocard, et al.
Published: (2021-05-01)

NiH-catalysed proximal-selective hydroalkylation of unactivated alkenes and the ligand effects on regioselectivity
by: Xiao-Xu Wang, et al.
Published: (2022-04-01)

[¹⁸F]Difluorocarbene for positron emission tomography
by: Sap, JBI, et al.
Published: (2022)

Mechanistic Insights into First-row Late Transition Metal-catalysed (formal) Hydroamination of Unactivated Alkenes
by: Jérôme Hannedouche
Published: (2018-09-01)

Silyl radical-mediated late-stage hydrofunctionalisation of alkenes
by: Hell, SM
Published: (2020)

Cooperative Cu/azodiformate system-catalyzed allylic C–H amination of unactivated internal alkenes directed by aminoquinoline
by: Le Wang, et al.
Published: (2024-02-01)

Asymmetric fluorocyclizations of alkenes.
by: Wolstenhulme, JR, et al.
Published: (2014)

Origin of the Ligand Ring‐Size Effect on the Catalytic Activity of Cationic Calcium Hydride Dimers in the Hydrogenation of Unactivated 1‐Alkenes
by: Dr. Hui Zhu, et al.
Published: (2022-12-01)

Pyrroline synthesis via visible‐light‐promoted hydroimination of unactivated alkenes with N,N′‐dimethylpropylene urea as H‐donor
by: Cai, Sai-Hu, et al.
Published: (2020)

Palladium-catalyzed cross-coupling of unactivated alkenes with Acrylates: application to the synthesis of the C13-C21 fragment of Palmerolide A
by: Wen, Zhen-Kang, et al.
Published: (2013)

Efficient gold(I)/silver(I)-cocatalyzed cascade intermolecular N-Michael addition/intramolecular hydroalkylation of unactivated alkenes with α-ketones
by: Ya-Ping Xiao, et al.
Published: (2011-08-01)

An improved synthesis of iodohydrins from alkenes
by: Smietana, M, et al.
Published: (2000)

New late-stage strategies towards difluoromethylarenes
by: Sap, JBI
Published: (2020)

Markovnikov-Type Hydrotrifluoromethylchalcogenation of Unactivated Terminal Alkenes with [Me<sub>4</sub>N][XCF<sub>3</sub>] (X = S, Se) and TfOH
by: Jin Shi, et al.
Published: (2020-10-01)

NiH-catalyzed anti-Markovnikov hydroamidation of unactivated alkenes with 1,4,2-dioxazol-5-ones for the direct synthesis of N-alkyl amides
by: Bingnan Du, et al.
Published: (2022-12-01)