The SCL complex regulates c-kit expression in hematopoietic cells through functional interaction with Sp1.
The combinatorial interaction among transcription factors is believed to determine hematopoietic cell fate. Stem cell leukemia (SCL, also known as TAL1 [T-cell acute lymphoblastic leukemia 1]) is a tissue-specific basic helix-loop-helix (bHLH) factor that plays a central function in hematopoietic de...
Main Authors: | Lécuyer, E, Herblot, S, Saint-Denis, M, Martin, R, Begley, C, Porcher, C, Orkin, S, Hoang, T |
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Format: | Journal article |
Language: | English |
Published: |
2002
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