Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

Circulating and Tissue-Resident CD4+ T Cells With Reactivity to Intestinal Microbiota Are Abundant in Healthy Individuals and Function Is Altered During Inflammation

<h3>Background & Aims</h3> <p>Interactions between commensal microbes and the immune system are tightly regulated and maintain intestinal homeostasis, but little is known about these interactions in humans. We investigated responses of human CD4<sup>+</sup> T ce...

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Main Authors:	Hegazy, AN, West, NR, Stubbington, MJT, Wendt, E, Suijker, KIM, Datsi, A, This, S, Danne, C, Campion, S, Duncan, SH, Owens, BMJ, Uhlig, HH, McMichael, A, Bergthaler, A, Teichmann, SA, Keshav, S, Powrie, F
Format:	Journal article
Language:	English
Published:	Elsevier 2017

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