The activity of JmjC histone lysine demethylase KDM4A is highly sensitive to oxygen concentrations
The JmjC histone lysine demethylases (KDMs) are epigenetic regulators involved in the removal of methyl groups from post-translationally modified lysyl residues within histone tails, modulating gene transcription. These enzymes require molecular oxygen for catalytic activity and, as 2-oxoglutarate (...
| 主要な著者: | , , , , |
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| フォーマット: | Journal article |
| 出版事項: |
American Chemical Society
2017
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