The activity of JmjC histone lysine demethylase KDM4A is highly sensitive to oxygen concentrations

The activity of JmjC histone lysine demethylase KDM4A is highly sensitive to oxygen concentrations

The JmjC histone lysine demethylases (KDMs) are epigenetic regulators involved in the removal of methyl groups from post-translationally modified lysyl residues within histone tails, modulating gene transcription. These enzymes require molecular oxygen for catalytic activity and, as 2-oxoglutarate (...

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Bibliographic Details
Main Authors:	Hancock, R, Masson, N, Dunne, K, Flashman, E, Kawamura, A
Format:	Journal article
Published:	American Chemical Society 2017

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