Frontline: Optimal T cell activation requires the engagement of CD6 and CD166
The T cell surface glycoprotein, CD6 binds CD166 in the first example of an interaction between a scavenger receptor cysteine-rich domain and an immunoglobulin-like domain. We report that in human these proteins interact with a KD =0.4-1.0 μM and Koff ≥0.4-0.63 s-1, typical of many leukocyte membran...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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