Frontline: Optimal T cell activation requires the engagement of CD6 and CD166

Frontline: Optimal T cell activation requires the engagement of CD6 and CD166

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The T cell surface glycoprotein, CD6 binds CD166 in the first example of an interaction between a scavenger receptor cysteine-rich domain and an immunoglobulin-like domain. We report that in human these proteins interact with a KD =0.4-1.0 μM and Koff ≥0.4-0.63 s-1, typical of many leukocyte membran...

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Príomhchruthaitheoirí:	Hassan, N, Barclay, N, Brown, M
Formáid:	Journal article
Teanga:	English
Foilsithe / Cruthaithe:	2004

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