Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer

Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer

<p><strong>Background</strong></p> <p>Polygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. We estimated the benefit of additional SNPs on performance of a previously validated PHS (PHS46).</p> <p><strong>Mater...

Mô tả đầy đủ

Chi tiết về thư mục
Những tác giả chính:	Karunamuni, RA, Huynh-Le, M-P, Fan, CC, Neal, DE, Hamdy, FC, Travis, RC, Mills, IG, Et al.
Tác giả khác:	UKGPCS collaborators
Định dạng:	Journal article
Ngôn ngữ:	English
Được phát hành:	Springer Nature 2021

Những quyển sách tương tự

Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score
Bằng: Huynh-Le, M, et al.
Được phát hành: (2022)

The effect of sample size on polygenic hazard models for prostate cancer
Bằng: Karunamuni, RA, et al.
Được phát hành: (2020)

Polygenic hazard score for prostate cancer risk stratification: validation in additional longitudinal cohorts
Bằng: Tye, K, et al.
Được phát hành: (2019)

A genetic risk score to personalize prostate cancer screening, applied to population data
Bằng: Huynh-Le, M-P, et al.
Được phát hành: (2020)

Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
Bằng: Huynh-Le, M, et al.
Được phát hành: (2021)

African-specific improvement of a polygenic hazard score for age at diagnosis of prostate cancer
Bằng: Karunamuni, RA, et al.
Được phát hành: (2020)

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts.
Bằng: Seibert, TM, et al.
Được phát hành: (2018)

Polygenic hazard score is associated with prostate cancer in multi-ethnic populations
Bằng: Minh-Phuong Huynh-Le, et al.
Được phát hành: (2021-02-01)

Evaluating approaches for constructing polygenic risk scores for prostate cancer in men of African and European ancestry
Bằng: Darst, BF, et al.
Được phát hành: (2023)

Robustification of GWAS to explore effective SNPs addressing the challenges of hidden population stratification and polygenic effects
Bằng: Zobaer Akond, et al.
Được phát hành: (2021-06-01)

Demographic history mediates the effect of stratification on polygenic scores
Bằng: Arslan A Zaidi, et al.
Được phát hành: (2020-11-01)

Performance of polygenic risk scores in screening, prediction, and risk stratification: secondary analysis of data in the Polygenic Score Catalog
Bằng: Harry Hemingway, et al.
Được phát hành: (2023-07-01)

Performance of African-ancestry-specific polygenic hazard score varies according to local ancestry in 8q24
Bằng: Karunamuni, RA, et al.
Được phát hành: (2021)

Polygenic risk and hazard scores for Alzheimer's disease prediction
Bằng: Leonenko, G, et al.
Được phát hành: (2019)

Polygenic hazard score, amyloid deposition and Alzheimer's neurodegeneration
Bằng: Tan, Chin Hong, et al.
Được phát hành: (2020)

Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Bằng: Itziar de Rojas, et al.
Được phát hành: (2021-06-01)

A genetic hazard score to personalize prostate cancer screening, applied to population data
Bằng: Huynh-Le, M-P, et al.
Được phát hành: (2019)

Prostate cancer polygenic risk score and prediction of lethal prostate cancer
Bằng: Robert J. Klein, et al.
Được phát hành: (2022-04-01)

Author Correction: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Bằng: Itziar de Rojas, et al.
Được phát hành: (2023-02-01)

Evaluating the prognostic performance of a polygenic risk score for breast cancer risk stratification
Bằng: Maria Olsen, et al.
Được phát hành: (2021-12-01)

An early-onset specific polygenic risk score optimizes age-based risk estimate and stratification of prostate cancer: population-based cohort study
Bằng: Yifei Cheng, et al.
Được phát hành: (2024-04-01)

Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification
Bằng: Xinan Wang, et al.
Được phát hành: (2024-02-01)

A polygenic risk score for nasopharyngeal carcinoma shows potential for risk stratification and personalized screening
Bằng: Yong-Qiao He, et al.
Được phát hành: (2022-04-01)

Alzheimer's polygenic hazard score in SuperAgers: SuperGenes or SuperResilience?
Bằng: Barbara E. Spencer, et al.
Được phát hành: (2022-01-01)

Assessment of a polygenic hazard score for the onset of pre-clinical Alzheimer’s disease
Bằng: Michael Vacher, et al.
Được phát hành: (2022-05-01)

Evaluation of Polygenic Risk Scores for Prediction of Prostate Cancer in Korean Men
Bằng: Jong Jin Oh, et al.
Được phát hành: (2020-10-01)

Polygenic risk and rare variant gene clustering enhance cancer risk stratification for breast and prostate cancers
Bằng: Joon Ho Kang, et al.
Được phát hành: (2024-10-01)

Polygene Risk Scores
Bằng: James Woodward, et al.
Được phát hành: (2023-07-01)

Risk Stratification for Bipolar Disorder Using Polygenic Risk Scores Among Young High-Risk Adults
Bằng: Silvia Biere, et al.
Được phát hành: (2020-10-01)

Caspase-8 gene SNPs in prostate cancer susceptibility a replication study
Bằng: Parry, M, et al.
Được phát hành: (2010)

Polygenic Hazard Score Associated Multimodal Brain Networks Along the Alzheimer’s Disease Continuum
Bằng: Kaicheng Li, et al.
Được phát hành: (2021-09-01)

Using polygenic scores in social science research: Unraveling childlessness
Bằng: Verweij, RM, et al.
Được phát hành: (2019)

Polygenic risk score for tumor aggressiveness and early-onset prostate cancer in Asians
Bằng: Sang Hun Song, et al.
Được phát hành: (2023-01-01)

Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score
Bằng: Aaron P. Thrift, et al.
Được phát hành: (2023-01-01)

Risk stratification for hepatocellular cancer among patients with cirrhosis using a hepatic fat polygenic risk score.
Bằng: Aaron P Thrift, et al.
Được phát hành: (2023-01-01)

Polygenic prediction of occupational status GWAS elucidates genetic and environmental interplay in intergenerational transmission, careers and health in UK Biobank
Bằng: Akimova, ET, et al.
Được phát hành: (2024)

Integration of risk factor polygenic risk score with disease polygenic risk score for disease prediction
Bằng: Hyein Jung, et al.
Được phát hành: (2024-02-01)

The sociogenomics of polygenic scores of reproductive behavior and their relationship to other fertility traits
Bằng: Mills, M, et al.
Được phát hành: (2018)

Polygenic inheritance, GWAS, polygenic risk scores, and the search for functional variants
Bằng: Crouch, DJM, et al.
Được phát hành: (2020)

Multi-PGS enhances polygenic prediction by combining 937 polygenic scores
Bằng: Clara Albiñana, et al.
Được phát hành: (2023-08-01)