Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer

<p><strong>Background</strong></p> <p>Polygenic hazard scores (PHS) can identify individuals with increased risk of prostate cancer. We estimated the benefit of additional SNPs on performance of a previously validated PHS (PHS46).</p> <p><strong>Mater...

Полное описание

Библиографические подробности
Главные авторы: Karunamuni, RA, Huynh-Le, M-P, Fan, CC, Neal, DE, Hamdy, FC, Travis, RC, Mills, IG, Et al.
Другие авторы: UKGPCS collaborators
Формат: Journal article
Язык:English
Опубликовано: Springer Nature 2021