Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.

Investigation of susceptibility loci identified in the UK rheumatoid arthritis whole-genome scan in a further series of 217 UK affected sibling pairs.

OBJECTIVE: A previous whole-genome scan (WGS) of 182 UK rheumatoid arthritis (RA) affected sibling pair (ASP) families suggested linkage to HLA and 11 other chromosome regions. Replication of such findings in an independent cohort can help to distinguish true linkages from false-positive linkages....

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Autores principales: Eyre, S, Barton, A, Shephard, N, Hinks, A, Brintnell, W, MacKay, K, Silman, A, Ollier, W, Wordsworth, P, John, S, Worthington, J
Formato: Journal article
Lenguaje:English
Publicado: 2004

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