Ion channel mechanisms of rat tail artery contraction-relaxation by menthol involving, respectively, TRPM8 activation and L-type Ca2+ channel inhibition

Transient receptor potential melastatin 8 (TRPM8) is the principal cold and menthol receptor channel. Characterized primarily for its cold-sensing role in sensory neurons, it is expressed and functional in several nonneuronal tissues, including vasculature. We previously demonstrated that menthol ca...

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Main Authors: Melanaphy, D, Johnson, C, Kustov, M, Watson, C, Borysova, L, Burdyga, T, Zholos, A
格式: Journal article
语言:English
出版: American Physiological Society 2016