Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia.

Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia.

Children with Down syndrome (DS) up to the age of 4 years are at a 150-fold excess risk of developing myeloid leukemia (ML-DS). Approximately 4%-5% of newborns with DS develop transient myeloproliferative disorder (TMD). Blast cell structure and immunophenotype are similar in TMD and ML-DS. A mutati...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Alford, K, Reinhardt, K, Garnett, C, Norton, A, Böhmer, K, von Neuhoff, C, Kolenova, A, Marchi, E, Klusmann, J, Roberts, I, Hasle, H, Reinhardt, D, Vyas, P
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2011

Ижил төстэй зүйлс

GATA1 Mutation In Transient Leukemia (TL) and Myeloid Leukemia of Down Syndrome
-н: Reinhardt, K, зэрэг
Хэвлэсэн: (2010)

GATA1 Mutation In Transient Leukemia (TL) and Myeloid Leukemia of Down Syndrome
-н: Reinhardt, K, зэрэг
Хэвлэсэн: (2010)

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia
-н: Maroz, A, зэрэг
Хэвлэсэн: (2014)

GATA1s induces hyperproliferation of eosinophil precursors in Down syndrome transient leukemia.
-н: Maroz, A, зэрэг
Хэвлэсэн: (2014)

GATA1 and cooperating mutations in myeloid leukaemia of Down syndrome
-н: Garnett, C, зэрэг
Хэвлэсэн: (2019)

Acute megakaryoblastic leukaemia (AMKL) and transient myeloproliferative disorder (TMD) in Down syndrome: a multi-step model of myeloid leukaemogenesis.
-н: Roy, A, зэрэг
Хэвлэсэн: (2009)

Analysis of JAK3, JAK2, and C-MPL mutations in transient myeloproliferative disorder and myeloid leukemia of Down syndrome blasts in children with Down syndrome.
-н: Norton, A, зэрэг
Хэвлэсэн: (2007)

Myeloid leukemia in children 4 years or older with Down syndrome often lacks GATA1 mutation and cytogenetics and risk of relapse are more akin to sporadic AML.
-н: Hasle, H, зэрэг
Хэвлэсэн: (2008)

GATA1 mutation and trisomy 21 are required only in haematopoietic cells for development of transient myeloproliferative disorder.
-н: Carpenter, E, зэрэг
Хэвлэсэн: (2005)

JAK mutations in Down syndrome - associated transient myeloproliferative disorder and acute megakaryocytic leukemia
-н: Vyas, P, зэрэг
Хэвлэсэн: (2008)

Low-dose cytarabine to prevent myeloid leukemia in children with Down syndrome: TMD Prevention 2007 study
-н: Marius Flasinski, зэрэг
Хэвлэсэн: (2018-07-01)

Transient myeloproliferative disorder in Down′s syndrome
-н: Vinayak Y Kshirsagar, зэрэг
Хэвлэсэн: (2012-01-01)

Mechanisms of progression of myeloid preleukemia to transformed myeloid leukemia in children with Down syndrome
-н: Labuhn, M, зэрэг
Хэвлэсэн: (2019)

GATA1 mutation analysis demonstrates two distinct primary leukemias in a child with down syndrome; implications for leukemogenesis.
-н: Hellebostad, M, зэрэг
Хэвлэсэн: (2005)

Abnormalities in the myeloid progenitor compartment in Down syndrome fetal liver precede acquisition of GATA1 mutations.
-н: Tunstall-Pedoe, O, зэрэг
Хэвлэсэн: (2008)

Severe TMD/AMKL with GATA1 mutation in a stillborn fetus with Down syndrome.
-н: Heald, B, зэрэг
Хэвлэсэн: (2007)

DNMT3A mutations are rare in childhood acute myeloid leukemia
-н: Felicitas Thol, зэрэг
Хэвлэсэн: (2011-08-01)

Transient Myeloproliferative Disorder and Down Syndrome Is there a link?
-н: Zenaida S. Reyes, зэрэг
Хэвлэсэн: (2012-11-01)

Guideline for management of non-Down syndrome neonates with a myeloproliferative disease on behalf of the I-BFM AML Study Group and EWOG-MDS
-н: Eline J.M. Bertrums, зэрэг
Хэвлэсэн: (2021-12-01)

Acute leukemias in children with Down syndrome.
-н: Zwaan, C, зэрэг
Хэвлэсэн: (2010)

How do Gata1 and cohesin gene mutations contribute to the development of myeloid leukaemia?
-н: Garnett, C
Хэвлэсэн: (2020)

Sensitive, rapid diagnostic test for transient abnormal myelopoiesis and myeloid leukemia of Down syndrome
-н: Cruz Hernandez, D, зэрэг
Хэвлэсэн: (2020)

GATA1-mutant clones are frequent and often unsuspected in babies with Down syndrome: identification of a population at risk of leukemia.
-н: Roberts, I, зэрэг
Хэвлэсэн: (2013)

Analysis of GATA-1 mutations in chronic myeloid leukaemia.
-н: Halsey, C, зэрэг
Хэвлэсэн: (2006)

Acute leukemias in children with Down syndrome.
-н: Zwaan, M, зэрэг
Хэвлэсэн: (2008)

Low frequency of type-I and type-II aberrations in myeloid leukemia of Down syndrome, underscoring the unique entity of this disease
-н: Marjolein Blink, зэрэг
Хэвлэсэн: (2012-04-01)

GATA1 mutational analysis in chronic myeloid leukaemia.
-н: Halsey, C, зэрэг
Хэвлэсэн: (2007)

Prevention and treatment of transformation of myeloproliferative neoplasms to acute myeloid leukemia
-н: Anand A. Patel, зэрэг
Хэвлэсэн: (2024-10-01)

Natural history of GATA-1 mutations in Down syndrome.
-н: Ahmed, M, зэрэг
Хэвлэсэн: (2003)

Myeloid pre-leukemia and leukemia of Down syndrome
-н: Cruz Hernandez, D, зэрэг
Хэвлэсэн: (2020)

Natural history of GATA1 mutations in Down syndrome.
-н: Ahmed, M, зэрэг
Хэвлэсэн: (2004)

Modelling the progression of a preleukemic stage to overt leukemia in children with down syndrome
-н: Labuhn, M, зэрэг
Хэвлэсэн: (2018)

Normal karyotype is a poor prognostic factor in myeloid leukemia of Down syndrome: a retrospective, international study
-н: Marjolein Blink, зэрэг
Хэвлэсэн: (2014-02-01)

Impact of mutant haemopoietic transcription factor GATA1s on haemopoiesis
-н: Vyas, P, зэрэг
Хэвлэсэн: (2017)

Guidelines for the investigation and management of Transient Leukaemia of Down Syndrome
-н: Tunstall, O, зэрэг
Хэвлэсэн: (2018)

Loss of DEP-1 (Ptprj) promotes myeloproliferative disease in FLT3-ITD acute myeloid leukemia
-н: Anne Kresinsky, зэрэг
Хэвлэсэн: (2018-11-01)

GATA2 mutations and overexpression in pediatric acute myeloid leukemia
-н: Zhenzhen Yang, зэрэг
Хэвлэсэн: (2019-08-01)

RSK1 is an exploitable dependency in myeloproliferative neoplasms and secondary acute myeloid leukemia
-н: Tim Kong, зэрэг
Хэвлэсэн: (2025-01-01)

Myeloproliferative Neoplasm or Reactive Process? A Rare Case of Acute Myeloid Leukemia and Transient Posttreatment Megakaryocytic Hyperplasia with JAK-2 Mutation
-н: Steven Wang, зэрэг
Хэвлэсэн: (2016-01-01)

Down myeloid disorders: a paradigm for childhood preleukaemia and leukaemia and insights into normal megakaryopoiesis.
-н: Vyas, P, зэрэг
Хэвлэсэн: (2006)