Cloning the gene for an inherited human disorder--chronic granulomatous disease--on the basis of its chromosomal location.
The gene that is abnormal in the X-linked form of the phagocytic disorder chronic granulomatous disease has been cloned without reference to a specific protein by relying on its chromosomal map position. The transcript of the gene is expressed in the phagocytic lineage of haematopoietic cells and is...
Principais autores: | Royer-Pokora, B, Kunkel, L, Monaco, A, Goff, S, Newburger, P, Baehner, R, Cole, F, Curnutte, J, Orkin, S |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
1986
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