Assessing the role of ADAM10 in Trastuzumab treatment and resistance

Assessing the role of ADAM10 in Trastuzumab treatment and resistance

<p>Overexpression of the HER2 receptor occurs in about 15-20% of all breast cancers and is correlated with poor prognosis. Trastuzumab (Herceptin®), a monoclonal antibody targeting HER2, was shown to prolong survival of these patients. However, primary or acquired resistance remains a drawback...

書目詳細資料
主要作者:	Feldinger, K
其他作者:	Kong, A
格式:	Thesis
語言:	English
出版:	2012
主題:	Cell Biology (see also Plant sciences) Oncology Biology

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