Tolerance and suppression in a primed immune system.
The induction of tolerance in a primed immune system would be valuable therapeutically, but has been difficult to achieve. Mice primed to multiple minor histoincompatible antigens (minors) are able to rapidly reject secondary grafts using either their CD4+ or CD8+ T-cell subpopulations. Short course...
Main Authors: | Marshall, SE, Cobbold, S, Davies, J, Martin, G, Phillips, J, Waldmann, H |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1996
|
Similar Items
-
Mechanisms of Peripheral Tolerance and Suppression Induced by Monoclonal Antibodies to CD4 and CD8
by: Cobbold, S, et al.
Published: (1996) -
Mechanisms of peripheral tolerance and suppression induced by monoclonal antibodies to CD4 and CD8.
by: Cobbold, S, et al.
Published: (1996) -
T cell regulation in adult transplantation tolerance.
by: Davies, J, et al.
Published: (1996) -
The induction of skin graft tolerance in major histocompatibility complex-mismatched or primed recipients: primed T cells can be tolerized in the periphery with anti-CD4 and anti-CD8 antibodies.
by: Cobbold, S, et al.
Published: (1990) -
T cell suppression in transplantation tolerance through linked recognition.
by: Davies, J, et al.
Published: (1996)