Synthesis of fluorinated alkyl aryl ethers by palladium-catalyzed C–O cross-coupling
Herein, we report a highly effective protocol for the cross-coupling of (hetero)aryl bromides with fluorinated alcohols using the commercially available precatalyst tBuBrettPhos Pd G3 and Cs2CO3 in toluene. This Pd-catalyzed coupling features a short reaction time, excellent functional group toleran...
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Bibliographic Details
| Main Authors: |
Szpera, R,
Isenegger, PG,
Ghosez, M,
Straathof, NJW,
Cookson, R,
Blakemore, DC,
Richardson, P,
Gouverneur, V |
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| Format: | Journal article
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| Language: | English |
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| Published: |
American Chemical Society
2020
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