Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

Varicella‐Zoster virus (VZV) causes chickenpox and shingles. Although the infection is associated with severe morbidity in some individuals, molecular mechanisms that determine innate immune responses remain poorly defined. We found that the cGAS/STING DNA sensing pathway was required for type I int...

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Bibliografische gegevens
Hoofdauteurs: Hertzog, J, Zhou, W, Fowler, G, Rigby, RE, Bridgeman, A, Blest, HT, Cursi, C, Chauveau, L, Davenne, T, Warner, BE, Kinchington, PR, Kranzusch, PJ, Rehwinkel, J
Formaat: Journal article
Taal:English
Gepubliceerd in: EMBO Press 2022