Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

Show other versions (1)

Varicella‐Zoster virus (VZV) causes chickenpox and shingles. Although the infection is associated with severe morbidity in some individuals, molecular mechanisms that determine innate immune responses remain poorly defined. We found that the cGAS/STING DNA sensing pathway was required for type I int...

Descrición completa

Detalles Bibliográficos
Main Authors:	Hertzog, J, Zhou, W, Fowler, G, Rigby, RE, Bridgeman, A, Blest, HT, Cursi, C, Chauveau, L, Davenne, T, Warner, BE, Kinchington, PR, Kranzusch, PJ, Rehwinkel, J
Formato:	Journal article
Idioma:	English
Publicado:	EMBO Press 2022

Títulos similares

Varicella-Zoster virus ORF9 Is an antagonist of the DNA sensor cGAS
por: Hertzog, J, et al.
Publicado: (2020)

Restriction by SAMHD1 limits cGAS/STING-dependent innate and adaptive immune responses to HIV-1
por: Maelfait, J, et al.
Publicado: (2016)

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1
por: Jonathan Maelfait, et al.
Publicado: (2016-08-01)

Deoxyguanosine is a TLR7 agonist
por: Davenne, T, et al.
Publicado: (2019)

Pneumonia a Varicella zoster Varicella zoster pneumonia
por: Carla Ferreira Santos, et al.
Publicado: (2010-06-01)

Varicella-zoster virus ORF 58 gene is dispensable for viral replication in cell culture
por: Nagaike Kazuhiro, et al.
Publicado: (2008-04-01)

Enzymatic Digestion Pattern of Varicella Zoster Virus ORF38 and ORF54 in Chickenpox Patients Using RFLP Technique
por: Hossein Keyvani, et al.
Publicado: (2016-01-01)

Neurexin 3 Regulates Synaptic Connections Between Central Amygdala Neurons and Excitable Cells of the Lateral Parabrachial Nucleus in Rats with Varicella Zoster Induced Orofacial Pain
por: Kramer PR, et al.
Publicado: (2024-07-01)

Sex differences underlying orofacial varicella zoster associated pain in rats
por: Crystal Stinson, et al.
Publicado: (2017-05-01)

Preventing varicella zoster infection in immunocompromised adults with varicella zoster–specific immunoglobulins
por: Daniel Gelman, et al.
Publicado: (2023-01-01)

Oncolytic varicella-zoster virus engineered with ORF8 deletion and armed with drug-controllable interleukin-12
por: Stephen J Russell, et al.
Publicado: (2024-03-01)

The varicella-zoster virus ORF16 protein promotes both the nuclear transport and the protein abundance of the viral DNA polymerase subunit ORF28
por: Huang-Shen Lin, et al.
Publicado: (2024-07-01)

Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus
por: Phillip R. Kramer, et al.
Publicado: (2018-10-01)

Mutagenesis of the Varicella-Zoster Virus Genome Demonstrates That VLT and VLT-ORF63 Proteins Are Dispensable for Lytic Infection
por: Shirley E. Braspenning, et al.
Publicado: (2021-11-01)

Varicella Zoster Virus Vasculopathies
por: J Gordon Millichap
Publicado: (2008-03-01)

Varicella Zoster Virus Encephalitis
por: Jared Lizzi, et al.
Publicado: (2019-11-01)

Herpes zoster ophthalmicus and varicella
por: Maria D, et al.
Publicado: (1974-01-01)

Pneumonia a Varicella zoster
por: Carla Ferreira Santos, et al.
Publicado: (2010-05-01)

Etymologia: Varicella Zoster Virus
Publicado: (2015-04-01)

Corrigendum: Aromatase Derived Estradiol Within the Thalamus Modulates Pain Induced by Varicella Zoster Virus
por: Phillip R. Kramer, et al.
Publicado: (2019-01-01)

The varicella-zoster virus ORF47 kinase interferes with host innate immune response by inhibiting the activation of IRF3.
por: Patricia Vandevenne, et al.
Publicado: (2011-02-01)

Simian Varicella Virus Pathogenesis in Skin during Varicella and Zoster
por: Ravi Mahalingam, et al.
Publicado: (2022-05-01)

Varicella vaccination alters the chronological trends of herpes zoster and varicella.
por: Po-Yuan Wu, et al.
Publicado: (2013-01-01)

Varicella Zoster Virus-Associated Meningitis as a Rebound Varicella Zoster Disease after Antiviral Discontinuation
por: Tetsuko Sato, et al.
Publicado: (2021-02-01)

A model of varicella-zoster reactivation
por: Jonathan E. Forde, et al.
Publicado: (2010-09-01)

Stroke after Varicella-Zoster Infection
por: J Gordon Millichap
Publicado: (2010-10-01)

Varicella Zoster Virus Optic Neuritis
por: J Gordon Millichap
Publicado: (2004-01-01)

Varicella Zoster Meningitis in an Immunized Child
por: J Gordon Millichap
Publicado: (2004-08-01)

Early presentation of varicella zoster infection
por: E O Obidike, et al.
Publicado: (1999-01-01)

Varicella zoster virus and cardiovascular diseases
por: Angelica Cersosimo, et al.
Publicado: (2022-09-01)

Meningo-encephalitis and herpes zoster-varicella
por: Kerawala SDD
Publicado: (1965-01-01)

Varicella zoster virus vaccines: an update
por: Gabutti G, et al.
Publicado: (2019-08-01)

The ‘Dynamic’ Marriage Between Varicella and Zoster
por: Pieter T. de Boer, et al.
Publicado: (2015-10-01)

Varicella‐zoster pneumonia with endobronchial lesions
por: Takuto Sueyasu, et al.
Publicado: (2021-10-01)

VARICELLA-ZOSTER VIRUS INFECTION IN PREGNANCY
por: Geta Vancea, et al.
Publicado: (2018-09-01)

Varicella-zoster virus early infection but not complete replication is required for the induction of chronic hypersensitivity in rat models of postherpetic neuralgia.
por: Benjamin E Warner, et al.
Publicado: (2021-07-01)

Persistent high frequencies of varicella-zoster virus ORF4 protein-specific CD4+ T cells after primary infection.
por: Jones, L, et al.
Publicado: (2006)

A novel recombinant ORF7-siRNA delivered by flexible nano-liposomes inhibits varicella zoster virus infection
por: Jiawei Pei, et al.
Publicado: (2023-09-01)

Disruption of PML nuclear bodies is mediated by ORF61 SUMO-interacting motifs and required for varicella-zoster virus pathogenesis in skin.
por: Li Wang, et al.
Publicado: (2011-08-01)

Comparative Analysis of the Simian Varicella Virus and Varicella Zoster Virus Genomes
por: Wayne L. Gray
Publicado: (2022-04-01)