Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

Varicella‐Zoster virus (VZV) causes chickenpox and shingles. Although the infection is associated with severe morbidity in some individuals, molecular mechanisms that determine innate immune responses remain poorly defined. We found that the cGAS/STING DNA sensing pathway was required for type I int...

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Bibliografiske detaljer
Main Authors: Hertzog, J, Zhou, W, Fowler, G, Rigby, RE, Bridgeman, A, Blest, HT, Cursi, C, Chauveau, L, Davenne, T, Warner, BE, Kinchington, PR, Kranzusch, PJ, Rehwinkel, J
Format: Journal article
Sprog:English
Udgivet: EMBO Press 2022