Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques.

Transient increase of interferon-stimulated genes and no clinical benefit by chloroquine treatment during acute simian immunodeficiency virus infection of macaques.

Simian immunodeficiency virus (SIV) infection leads to AIDS in experimentally infected Rhesus macaques similarly to HIV-infected humans. In contrast, SIV infection of natural hosts is characterized by a down-regulation of innate acute responses to the virus within a few weeks of infection and result...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Vaccari, M, Fenizia, C, Ma, Z, Hryniewicz, A, Boasso, A, Doster, M, Miller, C, Lindegardh, N, Tarning, J, Landay, A, Shearer, G, Franchini, G
Format: Journal article
Sprache:English
Veröffentlicht: Mary Ann Liebert Inc. 2014

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