GLUT2 (SLC2A2) is not the principal glucose transporter in human pancreatic beta cells: implications for understanding genetic association signals at this locus.
SLC2A2 encoding glucose transporter -2 (GLUT2) acts as the primary glucose transporter and sensor in rodent pancreatic islets and is widely assumed to play a similar role in humans. In healthy adults SLC2A2 variants are associated with elevated fasting plasma glucose (fpg) concentrations but physiol...
Main Authors: | McCulloch, L, van de Bunt, M, Braun, M, Frayn, K, Clark, A, Gloyn, A |
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Format: | Journal article |
Language: | English |
Published: |
2011
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