The role of dendritic cells in determining the breadth and epitope specificity of the initial CD8+ T cell response during acute HIV-1 infection
<p>During acute HIV-1 infection (AHI), CD8<sup>+</sup> T cell responses are initially induced to only 1-3 viral epitopes in many patients, and Nef-derived epitopes are very commonly targeted. The earliest CD8<sup>+</sup> T cell responses decrease in magnitude as virae...
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| Format: | Thesis |
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2016
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