Regulation of CXCR4 by the Notch ligand delta-like 4 in endothelial cells.
Gene-targeting studies have shown that Delta-like 4 (Dll4) is required for normal embryonic vascular remodeling, but the mechanisms underlying Dll4 regulatory functions are not well defined. We generated primary human umbilical vascular endothelial cells that express Dll4 protein to study Dll4 funct...
Main Authors: | Williams, C, Segarra, M, Sierra, M, Sainson, R, Tosato, G, Harris, A |
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Format: | Journal article |
Language: | English |
Published: |
2008
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