Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

<p><strong>Introduction:</strong><br /> Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Most such biomarker studies ar...

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Autores principales: Shi, L, Westwood, S, Baird, A, Winchester, L, Dobricic, V, Kilpert, F, Hong, S, Franke, A, Hye, A, Ashton, N, Morgan, A, Bos, I, Vos, S, Buckley, N, Kate, M, Scheltens, P, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, De Roeck, E, Sleegers, K, Frisoni, G, Blin, O, Richardson, J, Bordet, R, Molinuevo, J, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lleó, A, Alcolea, D, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Teunissen, C, Freund-Levi, Y, Frölich, L, Legido-Quigley, C, Barkhof, F, Blennow, K, Zetterberg, H, Baker, S, Morgan, B, Streffer, J, Visser, P, Bertram, L, Lovestone, S, Nevado-Holgado, A
Formato: Journal article
Lenguaje:English
Publicado: Elsevier 2019