Discovery and validation of plasma proteomic biomarkers relating to brain amyloid burden by SOMAscan assay

<p><strong>Introduction:</strong><br /> Plasma proteins have been widely studied as candidate biomarkers to predict brain amyloid deposition to increase recruitment efficiency in secondary prevention clinical trials for Alzheimer's disease. Most such biomarker studies ar...

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Auteurs principaux: Shi, L, Westwood, S, Baird, A, Winchester, L, Dobricic, V, Kilpert, F, Hong, S, Franke, A, Hye, A, Ashton, N, Morgan, A, Bos, I, Vos, S, Buckley, N, Kate, M, Scheltens, P, Vandenberghe, R, Gabel, S, Meersmans, K, Engelborghs, S, De Roeck, E, Sleegers, K, Frisoni, G, Blin, O, Richardson, J, Bordet, R, Molinuevo, J, Rami, L, Wallin, A, Kettunen, P, Tsolaki, M, Verhey, F, Lleó, A, Alcolea, D, Popp, J, Peyratout, G, Martinez-Lage, P, Tainta, M, Johannsen, P, Teunissen, C, Freund-Levi, Y, Frölich, L, Legido-Quigley, C, Barkhof, F, Blennow, K, Zetterberg, H, Baker, S, Morgan, B, Streffer, J, Visser, P, Bertram, L, Lovestone, S, Nevado-Holgado, A
Format: Journal article
Langue:English
Publié: Elsevier 2019