A camelid antibody fragment inhibits the formation of amyloid fibrils by human lysozyme.

Amyloid diseases are characterized by an aberrant assembly of a specific protein or protein fragment into fibrils and plaques that are deposited in various organs and tissues, often with serious pathological consequences. Non-neuropathic systemic amyloidosis is associated with single point mutations...

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Bibliographic Details
Main Authors: Dumoulin, M, Last, A, Desmyter, A, Decanniere, K, Canet, D, Larsson, G, Spencer, A, Archer, D, Sasse, J, Muyldermans, S, Wyns, L, Redfield, C, Matagne, A, Robinson, C, Dobson, C
Format: Journal article
Language:English
Published: 2003