Concise syntheses of the natural products (+)-sylvaticin and (+)-cis-sylvaticin.

Two concise syntheses of the natural products cis-sylvaticin and sylvaticin are reported, using oxidative cyclization methodology as the key step. A sequential solvolysis/hydride shift/intramolecular reduction cascade was used to establish the trans stereochemistry of one of the THF rings of sylvati...

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Detalles Bibliográficos
Autores principales: Donohoe, T, Harris, R, Williams, O, Hargaden, G, Burrows, J, Parker, J
Formato: Journal article
Lenguaje:English
Publicado: 2009
Descripción
Sumario:Two concise syntheses of the natural products cis-sylvaticin and sylvaticin are reported, using oxidative cyclization methodology as the key step. A sequential solvolysis/hydride shift/intramolecular reduction cascade was used to establish the trans stereochemistry of one of the THF rings of sylvaticin.