Concise syntheses of the natural products (+)-sylvaticin and (+)-cis-sylvaticin.

Two concise syntheses of the natural products cis-sylvaticin and sylvaticin are reported, using oxidative cyclization methodology as the key step. A sequential solvolysis/hydride shift/intramolecular reduction cascade was used to establish the trans stereochemistry of one of the THF rings of sylvati...

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Autori principali: Donohoe, T, Harris, R, Williams, O, Hargaden, G, Burrows, J, Parker, J
Natura: Journal article
Lingua:English
Pubblicazione: 2009
Descrizione
Riassunto:Two concise syntheses of the natural products cis-sylvaticin and sylvaticin are reported, using oxidative cyclization methodology as the key step. A sequential solvolysis/hydride shift/intramolecular reduction cascade was used to establish the trans stereochemistry of one of the THF rings of sylvaticin.