Pattern recognition by B cells: the role of antigen repetitiveness versus Toll-like receptors.
Viruses induce excellent antibody responses due to several intrinsic features. Their repetitive, organised structure is optimal for the activation of the B cell receptor (BCR), leading to an increased humoral response and a decreased dependence on T cell help. Viruses also trigger Toll-like receptor...
Main Authors: | Hinton, H, Jegerlehner, A, Bachmann, M |
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Format: | Journal article |
Language: | English |
Published: |
2008
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