Cytochrome P450/ABC transporter inhibition simultaneously enhances ivermectin pharmacokinetics in the mammal host and pharmacodynamics in Anopheles gambiae

Mass administration of endectocides, drugs that kill blood-feeding arthropods, has been proposed as a complementary strategy to reduce malaria transmission. Ivermectin is one of the leading candidates given its excellent safety profile. Here we provide proof that the effect of ivermectin can be boos...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Chaccour, CJ, Hammann, F, Alustiza, M, Castejon, S, Tarimo, BB, Abizanda, G, Irigoyen Barrio, Á, Martí Soler, H, Moncada, R, Bilbao, JI, Aldaz, A, Maia, M, Del Pozo, JL
Materyal Türü: Journal article
Dil:English
Baskı/Yayın Bilgisi: Springer Nature 2017