Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells.

Dendritic cells (DCs) are potent antigen-presenting cells that initiate protective T-cell immunity in mice. To study the immunogenicity of DCs in humans, we injected 9 healthy subjects subcutaneously with a control injection of autologous monocyte-derived, mature DCs, followed 4-6 weeks later by DCs...

Full description

Bibliographic Details
Main Authors: Dhodapkar, M, Steinman, R, Sapp, M, Desai, H, Fossella, C, Krasovsky, J, Donahoe, S, Dunbar, P, Cerundolo, V, Nixon, D, Bhardwaj, N
Format: Journal article
Language:English
Published: 1999