Butyrylcholinesterase K variant associated with higher enzyme activity in the temporal cortex of elderly patients.
There is evidence to suggest an involvement of the K variant of the butyrylcholinesterase gene (BCHE) in dementia. We have examined the relationship between BCHE genotype and butyrylcholinesterase (BuChE) activity in autopsy brain tissue. We studied 164 autopsy cases, 144 with dementia and 20 contro...
Main Authors: | Tasker, A, Ballard, C, Joachim, C, Warden, DR, Okello, E, Perry, R, Khan, N, Smith, A, Lehmann, D, Perry, E |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2008
|
Similar Items
-
Association of butyrylcholinesterase K variant with cholinesterase-positive neuritic plaques in the temporal cortex in late-onset Alzheimer's disease.
by: Lehmann, D, et al.
Published: (2000) -
The butyrylcholinesterase K variant and susceptibility to Alzheimer's disease.
by: Kehoe, P, et al.
Published: (1998) -
Rate of progression of cognitive decline in Alzheimer's disease: effect of butyrylcholinesterase K gene variation.
by: Holmes, C, et al.
Published: (2005) -
Butyrylcholinesterase K variant is associated with type 2 diabetes in UK Caucasians
by: Hashim, Y, et al.
Published: (2000) -
Flavonoids as Inhibitors of Human Butyrylcholinesterase Variants
by: Maja Katalinić, et al.
Published: (2014-01-01)