Accurate quantification of modified cyclic peptides without the need for authentic standards
There is a growing interest in the use of cyclic peptides as therapeutics, but their efficient production is often the bottleneck in taking them forward in the development pipeline. We have recently developed a method to synthesise azole-containing cyclic peptides using enzymes derived from differen...
Main Authors: | Adaba, R, Mann, G, Raab, A, Houssen, W, McEwan, A, Thomas, L, Tabudravu, J, Naismith, J, Jaspars, M |
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Format: | Journal article |
Published: |
Elsevier
2016
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