Synthesis of lipid-carbohydrate-peptidyl-RNA conjugates to explore the limits imposed by the substrate specificity of cell wall enzymes on the acquisition of drug resistance

Synthesis of lipid-carbohydrate-peptidyl-RNA conjugates to explore the limits imposed by the substrate specificity of cell wall enzymes on the acquisition of drug resistance

Conjugation of RNA with multiple partners to obtain mimics of complex biomolecules is limited by the identification of orthogonal reactions. Here, lipid-carbohydrate-peptidyl-RNA conjugates were obtained by post-functionalization reactions, solid-phase synthesis, and enzymatic steps, to generate mol...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Fonvielle, M, Bouhss, A, Hoareau, C, Patin, D, Mengin-Lecreulx, D, Iannazzo, L, Sakkas, N, El Sagheer, A, Brown, T, Ethève-Quelquejeu, M, Arthur, M
Format: Journal article
Język:English
Wydane: Wiley 2018

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