Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.

Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.

PURPOSE: The complement factor H (CFH) gene polymorphism Y402H (1277T-->C) has been associated with susceptibility to age-related macular degeneration (AMD). The purpose of this study was to confirm this association in a U.K. population, to determine whether the association holds for both geo...

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Detalhes bibliográficos
Main Authors: Sepp, T, Khan, J, Thurlby, D, Shahid, H, Clayton, D, Moore, A, Bird, A, Yates, JR
Formato: Journal article
Idioma:English
Publicado em: 2006

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