Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.
PURPOSE: The complement factor H (CFH) gene polymorphism Y402H (1277T-->C) has been associated with susceptibility to age-related macular degeneration (AMD). The purpose of this study was to confirm this association in a U.K. population, to determine whether the association holds for both geo...
Main Authors: | Sepp, T, Khan, J, Thurlby, D, Shahid, H, Clayton, D, Moore, A, Bird, A, Yates, JR |
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Formato: | Journal article |
Idioma: | English |
Publicado em: |
2006
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