Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.

Complement factor H variant Y402H is a major risk determinant for geographic atrophy and choroidal neovascularization in smokers and nonsmokers.

PURPOSE: The complement factor H (CFH) gene polymorphism Y402H (1277T-->C) has been associated with susceptibility to age-related macular degeneration (AMD). The purpose of this study was to confirm this association in a U.K. population, to determine whether the association holds for both geo...

Bibliografski detalji
Glavni autori:	Sepp, T, Khan, J, Thurlby, D, Shahid, H, Clayton, D, Moore, A, Bird, A, Yates, JR
Format:	Journal article
Jezik:	English
Izdano:	2006

Slični predmeti

Interaction of Human Complement Factor H Variants Tyr402 and His 402 with Leptospira spp.
od: Aldacilene Souza Silva, i dr.
Izdano: (2011-10-01)

LL-37 and hBD-2 in the gingival crevicular fluid of smokers and nonsmokers with periodontitis
od: Alessandra Barreto LOPES, i dr.
Izdano: (2021-12-01)

Histomorphometric analysis of gingival tissue in smokers and nonsmokers
od: Mundoor Manjunath Dayakar, i dr.
Izdano: (2015-01-01)

Choroidal Round Hyporeflectivities in Geographic Atrophy.
od: Eleonora Corbelli, i dr.
Izdano: (2016-01-01)

Comparative modeling of socio-economic burden among smokers, nonsmokers and former smokers
od: E. V. Radchenko, i dr.
Izdano: (2019-07-01)

Analysis of lipid profile in cancer patients, smokers, and nonsmokers
od: A Vikramsimha Reddy, i dr.
Izdano: (2016-01-01)

The relation of obesity with serum resistin levels in smoker and nonsmokers
od: Gül Gürsoy, i dr.
Izdano: (2012-01-01)

Assessment of salivary thiocyanate levels and pH in the saliva of smokers and nonsmokers with chronic periodontitis – A comparative study
od: C Naresh Kumar, i dr.
Izdano: (2021-01-01)

Comparing the Levels of Acute-Phase Reactants Between Smoker and Nonsmoker Diabetic Patients: More Predicted Risk for Cardiovascular Diseases in Smoker Compared to Nonsmoker Diabetics
od: Sepideh Rezaei-Adl, i dr.
Izdano: (2017-10-01)

Comparative study of smokers, ex-smokers, and nonsmokers who have experienced myocardial infarction
od: Nozawa Diogo, i dr.
Izdano: (2003-01-01)

The Role of the Complement Pathway in Clinical Progression of Geographic Atrophy
od: Rose Edmonds, MS, i dr.
Izdano: (2023-12-01)

Semen Quality Measures in Hookah and Cigarette Smokers Compared to Nonsmokers
od: Jehan Hamadneh, i dr.
Izdano: (2025-01-01)

Comparative study between smokers and nonsmokers regarding dry eye
od: Hosam Eldine Mohamed Khalil, i dr.
Izdano: (2018-01-01)

Regional lung function in nonsmokers and asymptomatic current and former smokers
od: Barbara Vogt, i dr.
Izdano: (2019-07-01)

Is Complement Factor H Tyr402His Variant a Potential Cause of Ankylosing Spondylitis?
od: Sacide Pehlivan, i dr.
Izdano: (2020-03-01)

Identification of an autoantibody panel to separate lung cancer from smokers and nonsmokers
od: Eylers Ellen, i dr.
Izdano: (2010-05-01)

Spectral domain-optical coherence tomography retinal biomarkers in choroidal neovascularization of multifocal choroiditis, myopic choroidal neovascularization, and idiopathic choroidal neovascularization
od: Rui Gao, i dr.
Izdano: (2021-01-01)

Screening of CRISPR/Cas base editors to target the AMD high-risk Y402H complement factor H variant
od: Minh Thuan Nguyen Tran, i dr.
Izdano: (2019-03-01)

Distinct effects of complement and of NLRP3- and non-NLRP3 inflammasomes for choroidal neovascularization
od: Jakob Malsy, i dr.
Izdano: (2020-12-01)

Mitochondrial mutational spectra in human bronchial ephithelial cells of smokers and nonsmokers
od: Coller, Hilary Ann, 1967-
Izdano: (2009)

Periodontal Status in Smokers and Nonsmokers: A Clinical, Microbiological, and Histopathological Study
od: Maddipati Sreedevi, i dr.
Izdano: (2012-01-01)

Comparison of gingival health status and salivary magnesium levels in smokers and nonsmokers
od: Tania Kusuma Wijaya, i dr.
Izdano: (2021-01-01)

Comparison of Spermatozoa Quality in Male Smokers and Nonsmokers of Iranian Infertile Couples
od: Mahshid Aryanpur, i dr.
Izdano: (2011-10-01)

Frequency of Porphyromonas gingivalis fimA in smokers and nonsmokers after periodontal therapy
od: Mariana Gouvêa Latini ABREU, i dr.
Izdano: (2019-04-01)

CFH Y402H polymorphism and response to intravitreal Ranibizumab in brazilian patients with neovascular age-related macular degeneration
od: Carlos Eduardo Veloso, i dr.

Choroidal neovascular membrane
od: Bhatt Nitul, i dr.
Izdano: (1998-01-01)

Complement factor H Y402H polymorphism results in diminishing CD4+ T cells and increasing C-reactive protein in plasma
od: Marie Krogh Nielsen, i dr.
Izdano: (2023-11-01)

Complement Factor H Y402H and LOC387715 A69S Polymorphisms in Association with Age-Related Macular Degeneration in Iran
od: Hossein Nazari Khanamiri, i dr.
Izdano: (2014-01-01)

Risk factors for myopic choroidal neovascularization-related macular atrophy after anti-VEGF treatment.
od: Ki Woong Bae, i dr.
Izdano: (2022-01-01)

Population Pharmacokinetics of Pegcetacoplan in Patients with Geographic Atrophy or Neovascular Age-related Macular Degeneration
od: Ryan L. Crass, PharmD, i dr.
Izdano: (2025-03-01)

Double focal choroidal excavation with choroidal neovascularization
od: Sashwanthi Mohan, i dr.
Izdano: (2025-01-01)

Bilateral Multifocal Choroidal Osteoma with Choroidal Neovascularization
od: Mousavi MirNaghi, i dr.
Izdano: (2015-01-01)

Tooth mortality in smokers and nonsmokers in a selected population in Sana'a, Yemen
od: Al-Bayaty, F.H., i dr.
Izdano: (2008)

Comparative study of hematological parameters among smokers and nonsmokers in Basra city, Iraq
od: Safa Mohammed Hussein, i dr.
Izdano: (2024-11-01)

Neural‐hematopoietic‐inflammatory axis in nonsmokers, electronic cigarette users, and tobacco smokers
od: Isabelle Ruedisueli, i dr.
Izdano: (2022-10-01)

Hematological and Inflammatory Parameters in Hookah Smokers and Nonsmokers: A Cross-sectional Study.
od: Sidra Latif, i dr.
Izdano: (2022-12-01)

Targeting Nonsmokers to Help Smokers Quit: Features of a Large-scale Intervention
od: Gary J Tedeschi, i dr.
Izdano: (2020-07-01)

Evaluation of salivary biomarkers of periodontitis among smokers and nonsmokers: A novel study
od: Abhilasha S Patil, i dr.
Izdano: (2020-01-01)

Tumor necrosis factor-&alpha; serum levels in healthy smokers and nonsmokers
od: Florin Petrescu, i dr.
Izdano: (2010-07-01)

The overlooked role of physical activity in mitigating the mortality risk in smokers and nonsmokers with COPD
od: Chi-Pang Wen, i dr.
Izdano: (2018-03-01)