Harnessing the potential of multimodal radiotherapy in prostate cancer
Radiotherapy in combination with androgen deprivation therapy (ADT) is a standard treatment option for men with localized and locally advanced prostate cancer. However, emerging clinical evidence suggests that radiotherapy can be incorporated into multimodality therapy regimens beyond ADT, in combin...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
Springer Nature
2020
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| _version_ | 1826273536033947648 |
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| author | Philippou, Y Sjoberg, H Lamb, AD Camilleri, P Bryant, RJ |
| author_facet | Philippou, Y Sjoberg, H Lamb, AD Camilleri, P Bryant, RJ |
| author_sort | Philippou, Y |
| collection | OXFORD |
| description | Radiotherapy in combination with androgen deprivation therapy (ADT) is a standard treatment option for men with localized and locally advanced prostate cancer. However, emerging clinical evidence suggests that radiotherapy can be incorporated into multimodality therapy regimens beyond ADT, in combinations that include chemotherapy, radiosensitizing agents, immunotherapy and surgery for the treatment of men with localized and locally advanced prostate cancer, and those with oligometastatic disease, in whom the low metastatic burden in particular might be treatable with these combinations. This multimodal approach is increasingly recognized as offering considerable clinical benefit, such as increased antitumour effects and improved survival. Thus, radiotherapy is becoming a key component of multimodal therapy for many stages of prostate cancer, particularly oligometastatic disease. |
| first_indexed | 2024-03-06T22:29:40Z |
| format | Journal article |
| id | oxford-uuid:57dffba4-30c6-4783-9b7d-7d8a31de2dee |
| institution | University of Oxford |
| language | English |
| last_indexed | 2024-03-06T22:29:40Z |
| publishDate | 2020 |
| publisher | Springer Nature |
| record_format | dspace |
| spelling | oxford-uuid:57dffba4-30c6-4783-9b7d-7d8a31de2dee2022-03-26T16:59:35ZHarnessing the potential of multimodal radiotherapy in prostate cancerJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:57dffba4-30c6-4783-9b7d-7d8a31de2deeEnglishSymplectic ElementsSpringer Nature2020Philippou, YSjoberg, HLamb, ADCamilleri, PBryant, RJRadiotherapy in combination with androgen deprivation therapy (ADT) is a standard treatment option for men with localized and locally advanced prostate cancer. However, emerging clinical evidence suggests that radiotherapy can be incorporated into multimodality therapy regimens beyond ADT, in combinations that include chemotherapy, radiosensitizing agents, immunotherapy and surgery for the treatment of men with localized and locally advanced prostate cancer, and those with oligometastatic disease, in whom the low metastatic burden in particular might be treatable with these combinations. This multimodal approach is increasingly recognized as offering considerable clinical benefit, such as increased antitumour effects and improved survival. Thus, radiotherapy is becoming a key component of multimodal therapy for many stages of prostate cancer, particularly oligometastatic disease. |
| spellingShingle | Philippou, Y Sjoberg, H Lamb, AD Camilleri, P Bryant, RJ Harnessing the potential of multimodal radiotherapy in prostate cancer |
| title | Harnessing the potential of multimodal radiotherapy in prostate cancer |
| title_full | Harnessing the potential of multimodal radiotherapy in prostate cancer |
| title_fullStr | Harnessing the potential of multimodal radiotherapy in prostate cancer |
| title_full_unstemmed | Harnessing the potential of multimodal radiotherapy in prostate cancer |
| title_short | Harnessing the potential of multimodal radiotherapy in prostate cancer |
| title_sort | harnessing the potential of multimodal radiotherapy in prostate cancer |
| work_keys_str_mv | AT philippouy harnessingthepotentialofmultimodalradiotherapyinprostatecancer AT sjobergh harnessingthepotentialofmultimodalradiotherapyinprostatecancer AT lambad harnessingthepotentialofmultimodalradiotherapyinprostatecancer AT camillerip harnessingthepotentialofmultimodalradiotherapyinprostatecancer AT bryantrj harnessingthepotentialofmultimodalradiotherapyinprostatecancer |