An efficient asymmetric synthesis of (-)-lupinine.
The asymmetric synthesis of (-)-lupinine was achieved in 8 steps, 15% overall yield and >99 : 1 dr from commercially available starting materials. The strategy used for the construction of the quinolizidine scaffold involved reaction of an enantiopure tertiary dibenzylamine via two sequential...
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Bibliographic Details
| Main Authors: |
Davies, S,
Fletcher, A,
Foster, E,
Houlsby, I,
Roberts, P,
Schofield, T,
Thomson, J |
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| Format: | Journal article
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| Language: | English |
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| Published: |
Royal Society of Chemistry
2014
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