An efficient asymmetric synthesis of (-)-lupinine.
The asymmetric synthesis of (-)-lupinine was achieved in 8 steps, 15% overall yield and >99 : 1 dr from commercially available starting materials. The strategy used for the construction of the quinolizidine scaffold involved reaction of an enantiopure tertiary dibenzylamine via two sequential...
Main Authors: | Davies, S, Fletcher, A, Foster, E, Houlsby, I, Roberts, P, Schofield, T, Thomson, J |
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Format: | Journal article |
Sprog: | English |
Udgivet: |
Royal Society of Chemistry
2014
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